全文获取类型
收费全文 | 337篇 |
免费 | 2篇 |
出版年
2019年 | 2篇 |
2015年 | 2篇 |
2014年 | 6篇 |
2013年 | 18篇 |
2012年 | 9篇 |
2011年 | 14篇 |
2010年 | 25篇 |
2009年 | 17篇 |
2008年 | 18篇 |
2007年 | 18篇 |
2006年 | 14篇 |
2005年 | 22篇 |
2004年 | 12篇 |
2003年 | 5篇 |
2002年 | 6篇 |
2001年 | 8篇 |
2000年 | 4篇 |
1999年 | 7篇 |
1998年 | 4篇 |
1997年 | 11篇 |
1996年 | 10篇 |
1995年 | 5篇 |
1994年 | 7篇 |
1993年 | 3篇 |
1992年 | 4篇 |
1990年 | 3篇 |
1989年 | 2篇 |
1988年 | 4篇 |
1987年 | 3篇 |
1986年 | 4篇 |
1985年 | 4篇 |
1983年 | 3篇 |
1981年 | 2篇 |
1980年 | 2篇 |
1978年 | 3篇 |
1977年 | 6篇 |
1976年 | 2篇 |
1975年 | 2篇 |
1974年 | 4篇 |
1973年 | 3篇 |
1972年 | 5篇 |
1971年 | 5篇 |
1966年 | 2篇 |
1963年 | 1篇 |
1959年 | 2篇 |
1958年 | 1篇 |
1957年 | 8篇 |
1956年 | 5篇 |
1955年 | 3篇 |
1954年 | 1篇 |
排序方式: 共有339条查询结果,搜索用时 15 毫秒
71.
PIERRE‐JEAN G. MALÉ JEAN‐FRANÇOIS MARTIN MAXIME GALAN VALÉRIE DEFFONTAINE JOSEF BRYJA JEAN‐FRANÇOIS COSSON JOHAN MICHAUX NATHALIE CHARBONNEL 《Biological journal of the Linnean Society. Linnean Society of London》2012,105(4):881-899
In the present study, a phylogeographical approach was developed to analyse the influence of selection and history on a major histocompatibility complex (Mhc) class II gene polymorphism in European bank vole (Myodes glareolus) populations. We focused on exon 2 of the Dqa gene because it is highly variable in a large array of species and appears to evolve under pathogen‐mediated selection in several rodent species. Using single‐strand conformation polymorphism analysis and sequencing techniques, 17 Dqa‐exon2 alleles, belonging to at least two different copies of Dqa gene, were detected over the distribution range of M. glareolus. Evidence of selection was found using molecular and population analyses. At the molecular level, we detected 13 codons evolving under positive selection pressures, most of them corresponding to regions coding for putative antigen binding sites of the protein. At the European level, we compared patterns of population structure for the Dqa‐exon2 and cytochrome b (cyt b) gene. We did not detect any spatial genetic structure among M. glareolus populations for the Dqa‐exon2. These results strongly differed from those obtained using the cyt b gene, which indicated a recent phylogeographical history closely linked to the last glacial events. Seven mitochondrial lineages have yet been described, which correspond to major glacial refugia. Altogether, our results revealed clear evidence of balancing selection acting on Dqa‐exon2 and maintaining polymorphism over large geographical areas despite M. glareolus history. It is thus likely that Mhc phylogeographical variability could have been shaped by local adaptation to pathogens. © 2012 The Linnean Society of London, Biological Journal of the Linnean Society, 2012, 105 , 881–899. 相似文献
72.
73.
DAMASE KHASA PATRICK POLLEFEYS AURA NAVARRO‐QUEZADA PIERRE PERINET JEAN BOUSQUET 《Molecular ecology resources》2005,5(4):920-923
Species‐specific microsatellite markers were obtained for the unambiguous recognition of five poplar species of ecological and commercial importance to eastern North America: the native species Populus balsamifera and Populus deltoides, the exotic species Populus maximowiczii, Populus nigra, Populus trichocarpa and their interspecific hybrids. Forty‐four of 71 tested primer pairs amplified simple sequence repeat (SSR) loci for all five taxa. Six of these loci showed non‐overlapping allelic diversity between species, including fixed differences. Together, they were useful to identify unambiguously the five taxa and to validate parental contributions in a group of hybrid progeny. These markers will be invaluable to detect gene flow from plantations of exotic poplar into adjacent stands of native species and between the two potentially hybridizing native species P. balsamifera and P. deltoides. 相似文献
74.
NATHALIE RAUFASTE ANNIE ORTH KHALID BELKHIR DAVID SENET CAROLE SMADJA STUART J. E. BAIRD † FRANÇOIS BONHOMME BARBARA DOD PIERRE BOURSOT 《Biological journal of the Linnean Society. Linnean Society of London》2005,84(3):593-616
We analysed the patterns of allele frequency change for ten diagnostic autosomal allozyme loci in the hybrid zone between the house mouse subspecies Mus musculus domesticus and M. m. musculus in central Jutland. After determining the general orientation of the clines of allele frequencies, we analysed the cline shapes along the direction of maximum gradient. Eight of the ten clines are best described by steep central steps with coincident positions and an average width of 8.9 km (support limits 7.6–12.4) flanked by tails of introgression, indicating the existence of a barrier to gene flow and only weak selection on the loci studied. We derived estimates of migration from linkage disequilibrium in the centre of the zone, and by applying isolation by distance methods to microsatellite data from some of these populations. These give concordant estimates of σ = 0.5–0.8 km generation . The barrier to gene flow is of the order of 20 km (support limits 14–28), and could be explained by selection of a few per cent at 43–120 underdominant loci that reduces the mean fitness in the central populations to 0.45. Some of the clines appear symmetrical, whereas others are strongly asymmetrical, and two loci appear to have escaped the central barrier to gene flow, reflecting the differential action of selection on different parts of the genome. Asymmetry is always in the direction of more introgression into musculus , indicating either a general progression of domesticus into the musculus territory, possibly mediated by differential behaviour, or past movement of the hybrid zone in the opposite direction, impeded by potential geographical barriers to migration in domesticus territory. © 2005 The Linnean Society of London, Biological Journal of the Linnean Society , 2005, 84 , 593–616. 相似文献
75.
76.
DIDIER BOUCHON CATHERINE SOUTY-GROSSET JEAN-PIERRE MOCQUARD AHMED CHENTOUFI PIERRE JUCHAULT 《Invertebrate reproduction & development.》2013,57(1-3):203-212
Summary Seasonal reproduction in Crustacea is synchronized by environmental cues (e.g., temperature and photoperiod). Two types of responses occur: (1) in reptant decapods, short photoperiods and low temperatures are necessary to induce vitellogenesis; (2) in natant decapods and in most peracarids, both high temperatures and long photoperiods promote the onset of reproduction. In this context studies on the biological clocks involved in photoperiodic time measurement were performed on two crustaceans: the ditch shrimp Palaemonetes varians and the woodlouse Armadillidium vulgare, which is distributed worldwide outside polar and intertropical areas. The most important feature of the photoperiodic response curves was the same mean lag time in response to photophase length ≤ 12 h: short photophases delayed breeding but did not prevent it (i.e., “short-day effect”). On the contrary, long photophases promoted the onset of reproduction (i.e., “long-day effect”) differently in P. varians and A. vulgare. In A. vulgare strains the shape of the photoperiodic response curve depended on latitudinal origin. Results of “resonance” experiments provided evidence of involvement of an endogenous circadian component in the photoperiodic clocks of the two species according to the internal coincidence model developed for insects. Seeing that relations between reproduction and moulting were different in the two species, we proposed the hypothesis of an evolutionary change in the transition from the sea to the continental environment. 相似文献
77.
PIERRE WACHE GERARD MAURICE MICHEL LUCIUS JEAN-FRANCOIS STOLTZ XIONG WANG 《Computer methods in biomechanics and biomedical engineering》2013,16(6):525-533
Abstract Mechanical forces influence endothelial cell's (EC) morphology and functions. In this work it was proposed a numerical analysis of steady laminar flows near a modelled monolayer of elastic ECs in order to determine the local distributions of mechanical forces on the surface and inside the cell. Numerical results showed that the flow induced non uniform mechanical stresses on cell surface and led to a cell deformation. These numerical results were compared with experimental measurements of the deformation of cultured human aortic endothelial cells under flow. It will be interesting to study eventual correlations between the distributions of biological receptors (cytoskeleton, adhesion molecules, etc.) and that of the non-uniform mechanical forces. 相似文献
78.
The debate about drag and reconfiguration of freshwater macrophytes: comparing results obtained by three recently discussed approaches 总被引:1,自引:0,他引:1
BERNHARD STATZNER NICOLAS LAMOUROUX VLADIMIR NIKORA PIERRE SAGNES 《Freshwater Biology》2006,51(11):2173-2183
1. The paper by Sand‐Jensen (2003 , Freshwater Biology, 48 , 271–283) on drag and reconfiguration of freshwater macrophytes stimulated comments and a reply about the use of variables in assessments of the drag coefficient (Cd) or the Reynolds number (Re) of such plants. Although the physical argument in this debate starts from the same equations, it diverges into approaches that address differently the dynamic behaviour of flexible plants in the boundary layer flow (the typical condition experienced by lotic macrophytes). 2. We compared three (potentially among many more) such different approaches using some preliminary experiments with Egeria densa by measuring drag (and other physical variables of interest) on (1) a single shoot exposed to varying flume flows; (2) a single shoot exposed to a constant flume flow, from which we subsequently pruned off pieces from the distal end; and (3) multiple shoots exposed to a constant flume flow after they had experienced replicated flow disturbances (causing shoot reconfiguration). 3. These experiments illustrated that the three approaches can produce opposite trends in the relationship between Cd and Re and that, for a given plant and flow, the Cd values obtained by these approaches can differ by about two orders of magnitude. Thus, conventions about the use of variables are required for experiments on drag and reconfiguration of freshwater macrophytes, otherwise the field will be plagued by a multitude of incomparable results. 相似文献
79.
80.
VINCENT PERRIER JEAN VANNIER PATRICK R. RACHEBOEUF† SYLVAIN CHARBONNIER DOMINIQUE CHABARD‡ DANIEL SOTTY‡ 《Palaeontology》2006,49(3):647-672
Abstract: Key aspects of the morphology, autecology, systematics and taphonomy of the crustacean syncarids from the Montceau Lagerstätte (Upper Carboniferous, Stephanian B; France) are presented. Palaeocaris secretanae is the most abundant faunal element of the Montceau biota and shows striking morphological similarities with Palaeocaris typus from the Mazon Creek Lagerstätte (Westphalian D; Illinois, USA). Palaeocaris secretanae was a shrimp‐like animal with a short head (no head shield), large mandibles, 14 trunk segments (the first one being reduced) and a fan‐like caudal termination. Both the body and the appendage design indicate abilities for crawling on the substratum (slender endopods) and for escape reaction (uropodal fan, pleonal flexibility), although swimming activities may have been reduced (trunk appendages with small flap‐like exopods). Details of the appendages involved in feeding, e.g. mandibles and maxillipeds, indicate poor ability for predation but point to an omnivorous detritus feeding mode. Poorly developed respiratory organs (small cylindrical epipods) suggest a relatively low level of locomotory activity. The field of vision may have been large and panoramic (stalked eyes). Rows of pores on 12 trunk segments are interpreted as possible sensory organs used for current detection. Females were brooding eggs (clusters of eggs preserved along anteroventral trunk). Microprobe analysis indicates that siderite is the major component of the nodules. Four events played a key‐role in the three‐dimensional preservation of syncarids: (1) rapid burial, (2) minimal decomposition, (3) phosphatic mineralization shortly after the animal's death and (4) nodule formation around the carcass. Palaeocaris secretanae is morphologically close to Recent syncarids such Anaspides tasmaniae (freshwater streams, Australia) in its general body plan and detailed anatomy, e.g. mouth parts, indicating morphological stasis in syncarids over more than 200 million years. 相似文献